Long-term administration of warfarn versus aspirin for improving the patency of infra-genicular bypass grafts

Fifty patients having infra-genicular bypass grafting were grouped into two groups: group [A] 25 patients were given Warfarin post-operatively, monitoring the dose by I.N.R estimation [target I.N.R: 2-3]; and Group B: 25 patients given aspirin 500 mg/day post operatively. The study has clarified that Warfarin therapy-compared with the aspirin therapy-does not increase the early, intermediate nor the late graft patency rate, and that Warfarin therapy is associated with increased hemorrhagic events, and necessitates life long regular dose monitoring [I. N. R]

peritoneo-venous [Denver] shunt in the management of intractable ascites in-patients with portal hypertension

The Denver Peritoneo-venous shunt was implanted in 15 patients with intractable ascites. The procedure was safe with no peri-operative mortality. It much improved the quality of life as regard with respiration, sleep and locomotion- in 60% of the patients. It also improved some of the biochemical abnormalities of those patients namely, serum albumin and serum creatinine levels. It avoids the patients the costly frequent hospitalizition, frequent intravenous albumin administration and the hazardous abdominal paracentesis